WebNov 29, 2012 · Dual-specificity phosphatases (DUSPs) is an emerging subclass of the protein tyrosine phosphatase gene superfamily, a heterogeneous group of protein phosphatases that can dephosphorylate both... WebMay 1, 2007 · Dual-specificity phosphatases (DUSPs) are a subclass of protein tyrosine phosphatases (PTPs) that specifically interact with and regulate mitogen-activated …
Dusps, to MAP Kinases and Beyond Ching-Yu Huang1* and Tse …
Many molecular mechanisms responsible for the cross-regulations between DUSPs and MAP kinases have been discussed (summarized in Figure 4). However, the possibility that typical DUSPs may dephosphorylate non-MAP kinase proteins must also be considered. During our characterization of DUSP4 … See more The dual-specificity phosphatase (DUSP) family proteins are so named for their ability to dephosphorylate both the threonine/serine and tyrosine residues of their substrates. This … See more DUSPs’ primary mode of action is the dephosphorylation of tyrosine and/or serine/threonine residues and the resulting activity regulation of their substrates. The physiological outcomes of DUSPs’ functions thus hinge … See more Signals from the MAP kinases are important for thymocyte development and helper T cell polarization (reviewed in [4]). In addition, several DUSPs have been found to be … See more WebAcademic Departments. Back; Academic Departments Alabama College of Osteopathic ... Annals of Simulation photography editing mouse draw pad
Dual-specificity phosphatases: therapeutic targets in cancer
http://samples.jbpub.com/9781284116595/9781284116595_FMxx_Secure.pdf WebDUSPs, to MAP kinases and beyond. Ching-Yu Huang1* and Tse-Hua Tan1,2. Abstract. Phosphatases are important regulators of intracellular signaling events, and their functions have been implicated in many biological processes. Dual-specificity phosphatases (DUSPs), whose family currently contains 25 members, are phosphatases that can ... Webtoward extending its discussion beyond the possibility of inferential (ecological) bias. Next, the chapter reviews observational studies based on individuals as units of … how many zeros are in the product 30 × 105