Biobank japan release of disease traits

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August undefined, 2024

WebNational Center for Biotechnology Information WebApr 10, 2024 · INTRODUCTION. Obesity is a chronic disease and an independent risk factor for many major diseases [()].Over the past 30 years, the prevalence of overweight as well as general and central obesity has soared in both men and women globally and in China [(2-4)].Unhealthy dietary habits are a well-established risk factor for obesity …

A cross-population atlas of genetic associations for 220 …

WebJan 3, 2024 · MR inference using our gut microbiome M-GWAS summary data and disease GWAS summary statistics from Biobank Japan found that Alistipes, which showed negative effects on blood triglyceride in the 4D ... inbox my mail

Overview of BioBank Japan follow-up data in 32 diseases

WebFeb 23, 2024 · as Biobank Japan (BBJ)8-10 or Taiwan Biobank (TWB)11. By increasing the sample size and demographic ... family disease history information of disease endpoints with TAPE 18. In two types of cancer: gastric ... Genome-wide study on 72,298 Korean individuals in Korean biobank data for 76 traits identifies hundreds of novel loci ... Web18 hours ago · Abstract. Reproduction involves a wide range of biological processes, including organ formation and development, neuroendocrine regulation, hormone production, and meiosis and mitosis. Infertility, the failure of reproduction, has become a major issue for human reproductive health and affects up to one in seven couples … WebFeb 8, 2024 · The BioBank Japan Project, launched in 2003, enrolled 200,000 patients with 47 target diseases, making it one of the largest hospital based biobanks in the world. inbox no facebook

National Center for Biotechnology Information

WebApr 11, 2024 · White blood cell (WBC) counts in peripheral blood are a quantitative trait, and increased or decreased counts are part of stereotypical disease process for AI disorders 13, 14. In general ... WebMar 1, 2024 · BioBank Japan (BBJ) was launched in 2003, establishing a large patient-oriented biobank in order to contribute to the implementation of personalized medicine. … in another world with my smartphone sub indoWebDec 10, 2024 · UK Biobank is a major prospective epidemiological study that is carrying out detailed multimodal brain imaging on 100,000 participants, and includes genetics and ongoing health outcomes. As a step forwards in understanding genetic influence on brain structure and function, in 2024 we published genome-wide associations of 3,144 brain … inbox not loading ig

"WebBackground: We established a patient-oriented biobank, BioBank Japan, with information on approximately 200,000 patients, suffering from any of 47 common diseases. This follow … " - Biobank japan release of disease traits

Biobank japan release of disease traits

Genome-wide study on 72,298 Korean individuals in Korean biobank …

WebJun 8, 2024 · The 42 diseases encompassed a wide range of disease categories: 13 neoplastic diseases, five cardiovascular diseases, four … WebBiobank Japan release of disease traits: 120: ebi-a: Datasets that satisfy minimum requirements imported from the EBI database of complete GWAS summary data: 2,585: …

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WebApr 15, 2024 · Here we report findings from 102,900 individuals across 36 human quantitative traits in the Taiwan Biobank (TWB), a major biobank effort that broadens … WebApr 4, 2024 · Results: In the Japanese genome-wide association study, we identified 10 loci that presented suggestive evidence for the association with the PA risk (P<1.0×10 −6).In the meta-analysis, we identified 5 genome-wide significant loci (1p13, 7p15, 11p15, 12q24, and 13q12; P<5.0×10 −8), including 3 of the suggested loci in the Japanese genome-wide …

WebIn 2003, BioBank Japan (BBJ) started developing one of the world’s largest disease biobanks, creating a foundation for research aimed at achieving medical care tailored to the individual traits of each patient. From a total of 260,000 patients representing 440,000 … Outline of BioBank Japan's Online Biological Sample Search System - … ISO Certifications - BioBank Japan Organizational Structure - BioBank Japan Advisory Board - BioBank Japan ELSI Committee - BioBank Japan Steps for Provision of Samples and Data - BioBank Japan NBDC’s Genomic Data and Clinical Information - BioBank Japan Serum Panels - BioBank Japan WebFeb 23, 2024 · To expand an atlas of genetic associations in non-European populations, we conducted 220 deep-phenotype genome-wide association studies (diseases, biomarkers and medication usage) in BioBank Japan ...

WebBioBank Japan (BBJ) was launched in 2003, establishing a large patient-oriented biobank in order to contribute to the imple- mentation of personalized medicine. WebApr 13, 2024 · The proportional hazards assumption was tested using Schoenfeld residuals. Follow-up time was calculated from the baseline date to diagnosis of T2D, death, loss to follow-up, or censoring date (30 June 2024, which was the end of follow-up for the current data release), whichever came first. Two approaches were used.

WebMar 21, 2024 · Growing evidence suggests that red meat consumption is a risk factor for cardiovascular health, with potential sex disparity. The metabolic mechanisms have not been fully understood. Using the UK Biobank, first we examined the associations of unprocessed red meat and processed meat with ischemic heart disease (IHD) mortality …

WebApr 15, 2024 · Genome-wide association studies (GWAS) have identified tens of thousands of genetic loci associated with human complex traits and diseases[1][1],[2][2]. However, the majority of GWAS were conducted in individuals of European ancestry[3][3]. Failure to capture global genetic diversity has limited biological discovery and impeded equitable … in another world with my smartphone s1Web14 Laboratory of Complex Trait Genomics, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan. [email protected]. 15 Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan. [email protected]. inbox not receiving mailWebJun 16, 2024 · We present and assess the UK Biobank (UKB) Polygenic Risk Score (PRS) Release, a set of PRSs for 28 diseases and 25 quantitative traits being made available on the individuals in UKB. We also release a benchmarking software tool to enable like-for-like performance evaluation for different PRSs for the same disease or trait. Extensive … inbox newsWebBioBank Japan, by publicly distributing DNA, serum, and clinical information, could be a fundamental infrastructure for the implementation of personalized medicine. Keywords: … in another world with my smartphone todos epWebJun 14, 2024 · We developed a unified MR analysis framework to analyze GWAS summary statistics from the Biobank Japan (BBJ) [15,16,17], the UK ... (release 5) involved 30,952 cases and 187,840 controls of ... We then excluded 27 disease traits with case sample size n cases < 10,000 in BBJ or UKB, 12 traits with inconsistent definitions in BBJ and UKB, … inbox not showing emails in outlookWebNov 21, 2024 · Genome-wide association study of the risk of chronic kidney disease and kidney-related traits in the Japanese population: J-Kidney-Biobank J Hum Genet. 2024 Nov 21. doi: 10.1038 ... we conducted a GWAS to identify loci related to multiple kidney-related traits in Japanese individuals. First, to detect loci associated with CKD, eGFR, ... inbox not refreshing in outlookWebNov 29, 2024 · in a curated set of human diseases and traits using a unique resource of 200,000 individuals with exome sequencing data from the UK Biobank. Methods and Results: We included 199,832 participants with a mean age of 68 at follow-up. Exome-wide gene-based tests were performed for 64 diseases and 23 quantitative traits using a … in another world with my smartphone tv tropes